oncologist

Catalan doctor revolutionised molecular mechanism understanding, saving countless lives

Joan Massagué's team at Sloan Kettering Institute open up possibility of new cancer treatments by finding out how tumors spread

A team of oncologists led by Joan Massagué has made a breakthrough in cancer research. The team´s new study, one which lasted six years, was published on the 24^th of March in the journal ‘Cell’. The study reveals the mechanics through which cancer cells evade the immune system´s defences and remain dormant for years, only to metastasise at a later time. Cancer cells do this by imitating stem cells, releasing a certain protein inhibitor which puts them in a hibernation-like state, making them undetectable by the immune system. The study also breaks with the more widely-held view of how cancer cells metastasise, and opens new doors for cures and treatment therapies. However, the solution is not so simple, warns Joan Massagué.