health

The governments of Catalonia, the Basque Country, Andalusia, Asturias and the Canaries have spoken out against the Spanish Executive's draft bill on the Protection of the Life of the Unborn and the Rights of the Pregnant Woman, presented in December 2013. This legislative reform, which still has to be approved in Parliament, aims to restrict the right of abortion only to cases of rape, incest or when the mother´s health is at serious risk. The reform of the People's Party (PP) is far more conservative than the previous laws from 2010 and 1985. It has raised a paramount opposition throughout Spanish society and also at European level. Catalonia and the 4 other Autonomous Communities that are not run by the PP presented this week a formal request to discuss this reform, as the Spanish Executive rejects talking about it with other parties and regional governments.

A team of surgeons at the Sant Joan de Déu Hospital in the Catalan capital successfully removed a tumour from a five year old child by first preparing and practicing the “highly complex” procedure on a 3D printed tumour. The child had neuroblastoma, a difficult cancer to extirpate because of the surrounding blood vessels and arteries. In such cases, testing the procedure in advance "is key" because it allows surgeons to study the most effective way of extracting the tumour without damaging other tissues, and to test the method before surgery. This has been possible thanks to the use of a 3D replica of the tumour.

Researchers from the University of Barcelona (UB) and the Catalan capital’s CELLEX Biomedical Research Centre (IDIBAPS-UB) have found the essential role played by cholesterol in cell mobility and tissue invasion, which also means its role in cancer propagation. In fact, this research, led by Professor Carles Enrich, is a key study for better understanding of cancer metastasis – the process in which cancer cells invade healthy tissues – and progresses the discussion on the relationship between cholesterol levels and cancer incidence. The paper is published in open access ‘Cell Reports’. In short they found that the so-called “bad” cholesterol (LDL cells) promotes cell mobility while “good” cholesterol (HDL cells) avoids cell propagation. The study opens new therapeutic paths to blocking cancer metastasis.

Following an appeal from the Spanish Government, the Constitutional Court has confirmed the cautionary halt adopted in January 2013 and it has now definitively banned the Catalan Executive's drug prescription fee. The measure had been adopted to reduce pharmaceutical spending by limiting superfluous drug demand in order to reduce the overall public spending. It was one of the austerity measures adopted by the Catalan Government in 2012 to reduce public deficit, in order to meet the strict deficit targets imposed by the Spanish Executive. The measure meant that Catalans had to pay a one-euro fee for each drug prescription, with a maximum of 60 euros per year and with many exceptions for people with chronic diseases, on low incomes and pensioners. On the same day, the Constitutional Court has backed the Catalan Executive's judicial fees, also appealed by Madrid.

A total of 23,825 patients have to wait longer than the maximum 6-month-period to undergo one of the 14 surgeries with a guaranteed waiting time, according to the Catalan Minister of Health, Boi Ruiz. In 2013, a total of 151,009 patients underwent one of these surgeries, 3,834 more than the previous year, which represents a 2.6% increase. The number of patients who still require one of these 14 procedures in December 2013 has increased by 6% and 4,261 people, reaching 75,075 with an average waiting time of 5.78 months. On the other hand, the waiting lists for all surgeries, including the 14 specific procedures, have fallen by about 7,000 people in 2013 compared to 2012.

Barcelona’s Hospital Clínic has installed the ‘Micra’ 24mm pacemaker - equivalent to the size of a one euro coin -  in 4 patients as part of a clinical trial involving 10 medical centres and 60 patients troughout the world. This innovative wireless system is minimally invasive since it does not require any surgical procedure but is implanted in the heart through the femoral vein using a catheter. Such a procedure can be performed within 30 minutes and also reduces the patients’ risks of future infections. According to the Medical Director of the Hospital, Josep Brugada, if the clinical study is successful, it will involve a “paradigm shift”. Experts estimate it could reach hospitals within the next two or three years.

A surgical team of the Hospital de Bellvitge in L’Hospitalet de Llobregat, Greater Barcelona, has successfully reconstructed the breasts of 22 women suffering from cancer in one single surgery. This world pioneer medical procedure, consisting in transplanting dorsal muscle on to the removed breast, allows patients to “turn the page” on the disease much more quickly, according to Joan Maria Vinyals, the Head of plastic surgery. Indeed, this “complete and radical reconstruction”, which includes the nipple and areola, avoids having to proceed to a second surgery and erases the usual trauma regarding aesthetic concerns. Leonor Garrido, one of the patients, stated that the technique “had improved a lot” her quality of life since she had her tumour removed and the breast entirely reconstructed immediatly after.

The Catalan Institute of Oncology (ICO) and Roche pharmaceutical company have signed an agreement stating that the Catalan public institute will pay for treatments against cancer depending on clinical results adapted to each specific patient. For now, the agreement provides that Roche will supply two drugs against the most common cancers, mostly breast and colon. According to the agreement, the probabilities of success will be thoroughly examined and if they meet the requirements, the Catalan Government will fully pay for the treatment. If not, Roche will assume the costs progressively according to the degree of success.

A clinical trial conducted in nine Catalan health care centres and published in the ‘British Medical Journal’ found that “in the case of mild respiratory infections such as acute bronchitis, there is a misuse of antibiotics, which is of no benefit to patients, and only helps increasing resistance to these drugs”. The study has been coordinated by the prestigious Vall d’Hebron Research Institute (VHIR). From 2010 to 2012, 416 patients, who showed several signs of acute bronchitis, were randomly assigned one of three different treatments. The main conclusion was that antibiotics, the most widely prescribed treatment for this type of illness, are ineffective. The study also showed that anti-inflammatory treatments increased in a minimal way the chances of ending coughs faster.

The Director of Barcelona’s Centre for Regenerative Medicine (CMRB), world-famous scientist Juan Carlos Izpisúa, resigned due to the lack of financial and political support from both Spanish and Catalan Governments. Such news was first published by Spanish newspaper ‘El País’ and then confirmed by sources in the research centre. Internationally, Izpisúa is considered to be one of the most esteemed and learned scientists in the field of stem cells. With the Director stepping down, the CMRB could well lose most of its current projects. Indeed, 18 of the 21 projects are the intellectual property of Izpisúa and might no longer be carried out in the Barcelona-based research centre if Izpisúa quit.

Thousands of people – 12,000 according to Barcelona’s local police and 200,000 according to the organisers – demonstrated on Sunday in the streets of Barcelona to protest against the Spanish and Catalan Governments’ austerity measures and “antisocial” budgets. Led by the platform ‘Prou Retallades’ (“Stop Budget Cuts”) , the UGT and CCOO trade-unions, as well as political parties and associations, citizens voiced their disapproval of the new pension reform, working fragility and the latest austerity measures. They also specifically protested against the Catalan and Spanish Governments’ budgets for 2014, which they consider “antisocial”. The demonstration organisers criticised the “blind obedience” of the Catalan and Spanish Executives to the European Commission and the Troika.

Researchers from Barcelona’s Centre for Regenerative Medicine (CMRB), the Catalan capital’s Hospital Clínic and the Salk Institute of California have successfully created three-dimensional renal structures which are virtually indistinguishable from embryonic kidneys. They have started creating kidney cells from human stem cells, and ultimately proven that these newly created cells could aggregate in vitro to form a “micro-kidney”. The team led by Juan Carlos Izpisúa, from the CMRB, said that this scientific breakthrough would facilitate the study of kidney diseases and enable scientists to work on new treatments. He added that this achievement was a great step towards developing therapies based on the use of stem cells.

Researchers of Barcelona-based Vall d’Hebron Hospital and Research Institute discovered some of the main causes of the Idiopathic Pulmonary Fibrosis, which were unknown before today. Vall d’Hebron’s study showed that a continuous exposure to feather pillows and duvets was one of the main causes of this illness as it favours the scarring of lung tissue. This disease provokes a progressive decline of lung function and leads to asphyxia because of the deterioration of the organ’s tissue. The study has been able to trace the diseases’ causes in half of the studied cases. Besides feather pillows and duvets, the persistent exposure to fungus and close contact with birds can also trigger the illness. The Catalan research allows for a new approach to the illness’ prevention and its diagnosis in the early stages. It also represents a completely new approach to this pathology in terms of treatment.

At the HIV Vaccine World Congress, which is taking place in Barcelona between the 7^th and 10^th October, Catalan researchers presented a vaccine prototype that has proven to be effective in clinical studies conducted with mice and monkeys. The vaccine stimulates the creation of antibodies and attacks infected cells. The prototype has been created by the Catalan programme to develop a vaccine against HIV, HIVACAT. According to the programme’s Scientific Director, Christian Brander, the vaccine could eventually also be used as a therapeutic treatment.

According to a medical study developed in Barcelona’s Hospital Clínic, fetuses conceived by assisted reproduction have changes in their heart and arteries, which begin even before birth and persist in the postnatal period. These changes represent a significant increase in cardiovascular risk in adulthood. However, the researchers point out that this situation is reversible from the beginning of life through a diet rich in omega3 and other factors. In addition, they strongly emphasised that this is only a risk factor and not a disease. The study leader, Eduard Gratacós, said that “it's a message of opportunity, not alarm”. Furthermore, they also recommend monitoring the blood pressure of these babies.